Marine Natural Products

Marine organisms can be considered the most recent source of bioactive natural products in relation to terrestrial plants and non-marine microorganisms. Their exploitation was dependent on the development of techniques for collecting samples and improving spectrometric, mainly NMR, and separation methods. Approximately 28,500 marine natural products had been identified by the end of 2016. Cytotoxic and anticancer properties account for the majority of biological activity reported for MNPs. This is not surprising considering the ecological role of MNPs as chemical defense. The fact that the main source of funds for MNP drug discovery research in the US was the NIH/NCI has been suggested by some authors as the main reason for the greater emphasis on antitumor activity

 

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